Peptides Are Insane
Jeff Nippard
Sep 28, 2026 15:30
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In this video, I take a deep dive into the world of peptides to find out which ones actually live up to the hype. I break down the science behind popular fat loss peptides like semaglutide, injury recovery peptides like BPC-157, and anti-aging peptides like epitalon, looking at what works, what the risks are, and where the evidence falls short.
Timestamps:
Post Credits:
Editing - Cat Senior
Graphics - Joseph Bullivant, Pat Carriere, Ishaan Mahtani, Cat Senior
Sound Editor - Iain Toms
Assistant Editors - Juampa Galarza
References:
Semaglutide
https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
GLP-1 Usage
https://news.gallup.com/poll/696599/obesity-rate-declining.aspx
Oral Semaglutide
https://pubmed.ncbi.nlm.nih.gov/40934115/
https://pubmed.ncbi.nlm.nih.gov/37385278/
Tirzepatide
https://www.nejm.org/doi/full/10.1056/NEJMoa2206038
Retatrutide
https://investor.lilly.com/news-releases/news-release-details/lillys-triple-agonist-retatrutide-delivered-powerful-weight-loss
Semaglutide Safety
https://pubmed.ncbi.nlm.nih.gov/38679221/
Energy Balance Model
https://pmc.ncbi.nlm.nih.gov/articles/PMC9071483/
Semaglutide and Lean Mass Loss
https://pmc.ncbi.nlm.nih.gov/articles/PMC11611443/
BPC-157
https://www.researchgate.net/publication/310460258
https://pubmed.ncbi.nlm.nih.gov/34324435/
https://pubmed.ncbi.nlm.nih.gov/39325560/
https://pubmed.ncbi.nlm.nih.gov/40131143/
Many Injuries Heal with Time
https://pubmed.ncbi.nlm.nih.gov/34874323/
Telomeres and Aging
https://pubmed.ncbi.nlm.nih.gov/35777725/
Epitalon / Epithalamin
https://pubmed.ncbi.nlm.nih.gov/14523363/
https://link.springer.com/article/10.1007/s10517-006-0365-z
Social Relationships
https://pmc.ncbi.nlm.nih.gov/articles/PMC2910600/
Exercise, Smoking, and Body Weight
https://pmc.ncbi.nlm.nih.gov/articles/PMC6207481/
Sleep
https://academic.oup.com/sleep/article/47/1/zsad253/7280269
Alcohol Consumption
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2802963
Entertainment
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