The Weird Reason Rabies Is So Deadly

Rabies is the one of the deadliest diseases we know of; if you don’t get treatment soon after getting exposed, you’re almost certain to die. But rabies’ intent isn’t actually to kill – it's to control. LEARN MORE ************** To learn more about this topic, start your googling with these keywords: - Neurotropic: infects nerve tissue - Post-exposure prophylaxis (PEP): preventative medical treatment started after exposure to a pathogen SUPPORT MINUTEEARTH ************************** If you like what we do, you can help us!: - Become our patron: https://patreon.com/MinuteEarth - Our merch: http://dftba.com/minuteearth - Our book: https://minuteearth.com/books - Sign up to our newsletter: http://news.minuteearth.com - Share this video with your friends and family - Leave us a comment (we read them!) CREDITS ********* Kate Yoshida | Script Writer, Narrator and Director Arcadi Garcia i Rius | Storyboard Artist Sarah Berman | Illustration, Video Editing and Animation Nathaniel Schroeder | Music MinuteEarth is produced by Neptune Studios LLC https://neptunestudios.info OUR STAFF ************ Lizah van der Aart • Sarah Berman • Cameron Duke Arcadi Garcia i Rius • David Goldenberg • Melissa Hayes Henry Reich • Ever Salazar • Leonardo Souza • Kate Yoshida OUR LINKS ************ Youtube | https://youtube.com/MinuteEarth TikTok | https://tiktok.com/@minuteearth Twitter | https://twitter.com/MinuteEarth Instagram | https://instagram.com/minute_earth Facebook | https://facebook.com/Minuteearth Website | https://minuteearth.com Apple Podcasts| https://podcasts.apple.com/us/podcast/minuteearth/id649211176 REFERENCES ************** Bastos, V., Pacheco, V., Rodrigues, É. D., et al. (2023). Neuroimmunology of rabies: New insights into an ancient disease. Journal of Medical Virology, 95(10), e29042. https://doi.org/10.1002/jmv.29042 Brookes, V. J., Dürr, S., & Ward, M. P. (2019). Rabies-induced behavioural changes are key to rabies persistence in dog populations: Investigation using a network-based model. PLoS neglected tropical diseases, 13(9), e0007739. https://doi.org/10.1371/journal.pntd.0007739 Fu, Z. F., & Jackson, A. A. C. (2005). Neuronal dysfunction and death in rabies virus infection. Journal of neurovirology, 11(1), 101-106. https://doi.org/10.1080/13550280590900445 Hueffer, K., Khatri, S., Rideout, et al. (2017). Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. Scientific reports, 7(1), 12818. https://doi.org/10.1038/s41598-017-12726-4 Jackson, A. C. (2016). Diabolical effects of rabies encephalitis. Journal of neurovirology, 22(1), 8-13. https://doi.org/10.1007/s13365-015-0351-1 Lafon, M. (2011). Evasive strategies in rabies virus infection. In Advances in virus research (Vol. 79, pp. 33-53). Academic Press. https://doi.org/10.1016/b978-0-12-387040-7.00003-2